StatiQinon helps to maintain normal cholesterol levels
Coenzyme Q10 and cholesterol are both synthesized from the same substance in the body. This implies that if the body's production of cholesterol is reduced by a statin, the body's production of coenzyme Q10 is reduced accordingly.
|3 capsules contain|
|Alpha linolenic acid from Flax seed oil||675 mg|
|Red yeast rice extract||150 mg|
|Coenzyme Q10||90 mg|
StatiQinon consists of capsules containing a unique blend of three ingredients which are an extract from Red yeast rice, coenzyme Q10 and alpha-linolenic acid (ALA) extracted from flaxseed oil which helps to maintain healthy blood cholesterol levels while at the same time it is also well tolerated.
Red yeast rice is a product made of the yeast Monascus purpureus which have been cultured on rice. This process produces a strong red colour. Red yeast rice contains 14 active compounds called monacolins. One of the monacolins (monacolin K) is able to effectively block the enzyme HMG-CoA reductase which is a step in the process leading to the production of both cholesterol and coenzyme Q10 in the body. Red yeast rice also contains unsaturated fatty acids and phytosterols.
Statins are synthetically manufactured drugs intended for lowering cholesterol, but there are also naturally occurring statins. For instance, the oyster mushroom naturally contains lovastatin. Lovastatin is also found naturally in red yeast rice. Randomized clinical trials have found natural statins to be both effective and well tolerated - also in most individuals who do not tolerate synthetic cholesterol lowering drugs.
ALA is short for ”alpha-linolenic acid”, a type of omega-3 fatty acid that is found in plants. ALA is an essential fatty acid meaning that it can't be produced by the body but must be obtained through the diet. Sources for ALA include canola, soy, and walnuts.
ALA is effective for maintaining normal cholesterol levels. Dietary ALA decreases circulating cholesterol, and increases cholesterol efflux in foam cells. ALA prevents cholesterol to be integrated in plaque /athero-sclerosis through the foam cells and into the arterial wall.
Coenzyme Q10 is a vitamin-like compound which practically all cells in the human body depend on in order to produce energy. The energy is made from a biochemical conversion of fat, carbohydrate, and protein into ATP (adenosine triphosphate), a molecule that stores energy. Coenzyme Q10 is a downstream product of the mevalonate pathway, just like cholesterol. Since coenzyme Q10 and cholesterol are both synthesized from the same substance, mevalo-nate, this implies that if the body's production of cholesterol is reduced by a statin, the body's production of coenzyme Q10 is reduced accordingly.
Atorvastatin decreases the coenzyme Q10 level in the blood of patients.
Ref. Arch. Neurol. 2004 Jun;61(6): 889-92.
What are statins?
Statins are a class of cholesterol-lowering drugs that work by inhibiting the enzyme HMG-CoA reductase, which is plays a central role in the liver’s synthesis of cholesterol. There are many different types of statins, some with a more potent LDL-lowering effect than others.
Statins inhibit the enzyme HGM-CoA reductase and its ability to produce mevalonate, which is an intermediate product in the multi-step synthesis of cholesterol. In what is often referred to as the mevalonate pathway, mevalonate would under normal circumstances undergo a number of biochemical transformations, eventually causing it to branch into several different compounds, including cholesterol dolichol and ubiquinone. Statins effectively block this process.